We performed meta-analysis to search for novel immune-response-related transcripts. Half the predicted protein sequences were functionally annotated using protein sequence datasets for several model and insect species. The reference transcriptome sequences were constructed, which consisted of 149,685 transcripts, and 194,174 predicted amino acid sequences. Reference transcriptome data are required to perform the meta-analyses using public RNA-Seq data and transcriptome analysis using newly sequenced RNA-Seq data. The Western honeybee ( Apis mellifera) is a representative species of honeybees. Therefore, it has been studied extensively in entomological research. It is vital to honey production and pollination. The honeybee is an economically and ecologically essential insect species and a critical social behavior model.
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